Buzon 4mg Tab (Risperidone)

Used For Schizophrenia. The mechanism of action of risperidone in schizophrenia is unclear. The drug’s therapeutic activity in schizophrenia could be mediated through a combination of dopamine Type 2 (D2) and serotonin Type 2 (5HT2) receptor antagonism. The clinical effect from risperidone results from the combined concentrations of risperidone and its major metabolite, 9-hydroxyrisperidone (paliperidone). Antagonism at receptors other than D2 and 5HT2 may explain some of the other effects of risperidone. Side Effects• Increased mortality in elderly patients with dementia-related psychosis • Cerebrovascular adverse events, including stroke, in elderly patients with dementia-related psychosis • Neuroleptic malignant syndrome • Tardive dyskinesia • Metabolic Changes (Hyperglycemia and diabetes mellitus, Dyslipidemia, and Weight Gain) • Hyperprolactinemia • Orthostatic hypotension • Falls • Leukopenia, neutropenia, and agranulocytosis • Potential for cognitive and motor impairment • Seizures • Dysphagia • Priapism • Disruption of body temperature regulation • Patients with Phenylketonuria . Drug Interactions; Fluoxetine , Paroxetine , Carbamazepine , Ranitidine , Cimetidine , Erythromycin , Amitriptyline , levodopa , ketoconazole , verapamil , furoseamide , paliperidone , dopamine agonists , rifampicin , anticholinergics.